Evaluating developmental motor plasticity with paired afferent stimulation
نویسندگان
چکیده
منابع مشابه
Cerebellum to motor cortex paired associative stimulation induces bidirectional STDP-like plasticity in human motor cortex
The cerebellum is crucially important for motor control and adaptation. Recent non-invasive brain stimulation studies have indicated the possibility to alter the excitability of the cerebellum and its projections to the contralateral motor cortex, with behavioral consequences on motor control and adaptation. Here we sought to induce bidirectional spike-timing dependent plasticity (STDP)-like mo...
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Background: Toddlers with celiac disease are at risk of developmental delay due to frequent hospitalization and food deprivation. But an appropriate program to improve development of these children does not exist. Aim: Determination of the effect of a developmental stimulation program on development of toddlers’ fine motor skills. Methods: This clinical trial conducted on 50 eligible 1-3 year-o...
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Interindividual response variability to various motor-cortex stimulation protocols has been recently reported. Comparative data of stimulation protocols with different modes of action is lacking. We aimed to compare the efficacy and response variability of two LTP-inducing stimulation protocols in the human motor cortex: anodal transcranial direct current stimulation (a-tDCS) and paired-associa...
متن کاملInduction of plasticity in the human motor cortex by paired associative stimulation.
Current models of motor cortical plasticity, developed in studies on experimental animals, emphasize the importance of the conjoint activity of somatosensory afferents and intrinsic motor cortical circuits. The hypothesis that an enduring change in excitability in the cortical output circuitry can be induced in the human motor cortex by a paired-stimulation protocol was tested. Low-frequency me...
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Paired associative stimulation (PASLTP) of the human primary motor cortex (M1) can induce LTP-like plasticity by increasing corticospinal excitability beyond the stimulation period. Previous studies showed that two consecutive PASLTP protocols interact by homeostatic metaplasticity, but animal experiments provided evidence that LTP can be augmented by repeated stimulation protocols spaced by ~3...
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ژورنال
عنوان ژورنال: Developmental Medicine & Child Neurology
سال: 2015
ISSN: 0012-1622
DOI: 10.1111/dmcn.12704